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| 骨髓间充质干细胞修复心肌损伤的研究进展 | |
| 引用本文： | 沈利水[综述],屈百鸣[审校]. 骨髓间充质干细胞修复心肌损伤的研究进展[J]. 心功能杂志, 2013, 0(5): 620-622 |
| 作者姓名： | 沈利水[综述] 屈百鸣[审校] |
| 作者单位： | [1]浙江中医药大学第二临床医学院,浙江杭州310014 [2]浙江省人民医院心内科,浙江杭州310014 |
| 摘 要： | 心肌梗死（MI）具有较高的死亡率，大面积MI后幸存的患者，常因心肌结构重构而逐渐发展为心力衰竭，预后往往欠佳。近来研究发现，骨髓间充质干细胞（bone marrow mesenchymal stemcells，BMSCs）作为多潜能干细胞，对受损的心肌具有积极的修复作用，为改善MI患者的预后提供了一个新途径。本文主要就BMSCs修复受损心肌的相关机制作一综述。 |
| 关 键 词： | 骨髓间充质干细胞 心肌梗死 损伤 修复 |
Research progress of bone marrow mesenchymal stem cells in the repair of myocardial injury |
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| Affiliation: | SHEN Li-shui, Qu Bai-ming2(1. Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; 2. Department of Cardiology, Zhejiang Provincial People＇s Hospital, Hangzhou 310014, Zhejiang, China) |
| Abstract: | Myocardial infarction （MI） has a high mortality. Survival of MI in patients usually gradually develops into heart failure due to myocardial remodeling. The prognosis is poor. Recent studies have shown that bone marrow tive effect on the damag mesenchymal stem cells （BMSCs）, a type of pluripotent stem cells, have a poslive effect on the damaged myocardium, which provides a therapeutic alternative for improving the prognosis of MI patients. This article mainly reviews the mechanism of BMSCs in cardiac repair. |
| Keywords: | bone marrow mesenchymal stem cells myocardial infarction injury repair |
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