喘憋性肺炎婴幼儿血清维生素A、D与肺功能的相关性

目的 了解喘憋性肺炎婴幼儿发作期儿童的血清25羟维生素D25(OH)D]和维生素A水平,分析其与肺功能、血清IgE之间的相关性,以进一步发现维生素A、D与婴幼儿喘憋性肺炎的关系.方法 调查2020年1月至2021年6月昆明医科大学第二附属医院6月～3岁符合喘憋性肺炎诊断标准的56名婴幼儿和50名匹配的健康婴幼儿,用酶...

Studies on the Correlation between Serum Vitamin A,D and Lung Function in Infants with Asthmatic Pneumonia

  Objective  To understand the serum levels of 25-hydroxyvitamin D 25 （OH） D] and vitamin A in infants with asthmatic pneumonia during the onset of pneumonia, so as to analyze their correlation with lung function and serum Ig E and to further discover vitamin A and D relationship with infantile asthmatic pneumonia.   Methods  Fifty-six infants and 50 matched healthy infants and young children who met the diagnostic criteria for asthmatic pneumonia from June to 3 in the Second Affiliated Hospital of Kunming Medical University from 2020 to 2021 were investigated, and enzyme-linked immunoassay was used to check serum 25 （OH） D and Ig E concentration. A pulmonary function meter was used to detect the tidal volume、respiratory rate, Inspiratory time, up to the peak volume of infants with asthmatic infants and young children. The differences in serum 25 （OH） D and vitamin A levels between the two groups of children were analyzed, and the correlation between serum 25 （OH） D and vitamin A levels in children with asthmatic pneumonia and the severity of acute attacks was analyzed.   Results  The serum 25 （OH） D and vitamin A concentrations of infants and young children in the asthmatic pneumonia group were （18.26±6.64） ng/ml and （0.20±0.09） ng/ml, respectively, which were significantly lower than those of the control group （25.28±3.48） ng/ml, （0.58±0.12） ng/ml, the difference was statistically significant （P < 0.01）. Serum 25 （OH） D levels were positively correlated with the tidal volume, respiratory rate, Inspiratory time , up to the peak volume in infants with onset （r = 0.364, 0.341, 0.369 and 0.548）, and negatively correlated with Ig E （r = -0.549）.   Conclusion  Children in the asthmatic pneumonia group had vitamin A and D deficiency, and serum vitamin A, 25 （OH） D asthmatic pneumonia episodes were associated.