Biological strategies expressed by different Streptococcus pyogenes strains: an explanation of the epidemiology |
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| Affiliation: | 1. Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel;2. IFIBYNE-UBA-CONICET and Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, C1428EHA Buenos Aires, Argentina;1. Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan City, Taiwan;2. National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County, Taiwan;3. Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan City, Taiwan;4. Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan City, Taiwan;5. Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan City, Taiwan;6. Department of Biotechnology and Laboratory Science in Medicine, School of Biomedical Science and Engineering, National Yang Ming University, Taipei, Taiwan;7. Environmental and Occupational Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |
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| Abstract: | ![]()
The numerous reports in the last ten years on the serious diseases caused by Streptococcus pyogenes indicate the continued significance of this pathogen. Furthermore, clinical studies and modern techniques have yielded new information on S. pyogenes and its pathogenic mechanisms. Although much still remains to be discovered about the biology S. pyogenes, two different strategies — the ‘epidemic’ and the ‘endemic’ strategy — can be seen in the interaction of different S. pyogenes strains with the human host. The challenges posed by these two groups of bacteria are also outlined. |
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