| 佐剂性关节炎大鼠的血常规 |
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| 引用本文： | 于飞,张浪,梁青,傅晟,张骏,吕昕泽,方珍文.佐剂性关节炎大鼠的血常规[J].中国比较医学杂志,2014,24(1):5-7. |
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| 作者姓名： | 于飞 张浪 梁青 傅晟 张骏 吕昕泽 方珍文 |
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| 作者单位： | 天津市临床药物关键技术重点实验室，天津医科大学药学院,南开大学药学院,天津市国际生物医药联合研究院,天津市国际生物医药联合研究院,天津市临床药物关键技术重点实验室，天津医科大学药学院,天津国际生物医药联合研究院,广西食品药品检验所 |
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| 基金项目： | 天津市科技计划项目创新园专项 |
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| 摘 要： | 目的分析并探讨佐剂性关节炎大鼠的血常规。方法采用完全弗氏佐剂诱导Wistar大鼠出现关节炎，全自动血液分析仪检测血常规。结果27个血常规检测指标中，与正常大鼠比较，佐剂性关节炎大鼠有14个指标有显著性差异（P〈0．05），分别为白细胞数、中性细胞数（比例）、淋巴细胞比例、单核细胞数，网织红细胞数（包括高、中、低荧光强度和未成熟的）以及红细胞平均体积、平均血红蛋白量、红细胞分布宽度标准差和变异系数。结论佐剂性关节炎大鼠白细胞明显上升，会出现类似于人类风湿性关节炎的慢性病性贫血。
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| 关 键 词： | 佐剂性关节炎 大鼠 血常规 |
| 收稿时间： | 2013/10/22 0:00:00 |
| 修稿时间： | 2013/12/4 0:00:00 |
Blood routine of adjuvant arthritis rats |
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| YU Fei,ZHANG Lang,LIANG Qing,FU Sheng,ZHANG Jun,LU Xin-ze and FANG Zhen-wen.Blood routine of adjuvant arthritis rats[J].Chinese Journal of Comparative Medicine,2014,24(1):5-7. |
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| Authors: | YU Fei ZHANG Lang LIANG Qing FU Sheng ZHANG Jun LU Xin-ze and FANG Zhen-wen |
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| Institution: | Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, Pharmacy College of Tianjin Medical University,College of Pharmacy, Nankai University,Tianjin International Joint Academy of Biotechnology,Tianjin International Joint Academy of Biotechnology,Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, Pharmacy College of Tianjin Medical University,Tianjin International Joint Academy of Biotechnology & Medicine,Guangxi Institute for Food and Drug Control |
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| Abstract: | Objective To analyze blood routine in adjuvant arthritis rats. Methods Complete Freund's adjuvant-induced arthritis models were established in Wistar rats, and detection of blood routine was carried out by the automatic blood analyzer. Results Compared to normal rats, 14 blood test indicators were significantly different in adjuvant-induced arthritis rats. Conclusion The leukocytes count was significantly increased in adjuvant-induced arthritis rats, and anemia of chronic disease similar to people rheumatoid arthritis appeared. |
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| Keywords: | adjuvant arthritis rats blood routine |
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