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| 食管癌患者SIL_(-2R)和IL_(-6)的研究 | |
| 引用本文： | 王东升,贺向荣,段震峰,郭超,周占国,杜英,沈元珊. 食管癌患者SIL_(-2R)和IL_(-6)的研究[J]. 肿瘤基础与临床, 1993, 0(2) |
| 作者姓名： | 王东升 贺向荣 段震峰 郭超 周占国 杜英 沈元珊 |
| 作者单位： | 河南医科大学微生物学与免疫学教研室，河南医科大学微生物学与免疫学教研室，河南医科大学微生物学与免疫学教研室，河南医科大学微生物学与免疫学教研室，河南医科大学微生物学与免疫学教研室，河南医科大学微生物学与免疫学教研室，河南医科大学微生物学与免疫学教研室 |
| 摘 要： | 本文对25例食管癌患者和31例健康对照者外周血单个核细胞(PBMC)经 PHA 刺激后 IL_(-6)产生能力和细胞培养上清中 SIL-_(2R)水平做了研究,同时检测了血清中 SIL_(-2R)水平。结果显示,食管癌患者产生 IL_(?)能力显著升高(P<0.001);食管癌患血清 SIL_(-2R)水平同健康者相比也显著升高(P<0.001),而细胞培养上清SIL_(-2R)浓度,两者比较差异无显著性(P>0.05)。 |
| 关 键 词： | 食管癌 可溶性白细胞介素_2受体(SIL_(-2R)) 白细胞介素_6(IL_(-6)) |
Study on Soluble Interleukin_(-2) Receptor and Interleukin_(-6) in Patients with Esophageal Carcinoma |
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| Wang Dongsheng. Study on Soluble Interleukin_(-2) Receptor and Interleukin_(-6) in Patients with Esophageal Carcinoma[J]. journal of basic and clinical oncology, 1993, 0(2) | |
| Authors: | Wang Dongsheng |
| Affiliation: | Wang Dongsheng Department of Microbiology and Immunology,Henan Medical University,Zhengzhou 450052 |
| Abstract: | The ability of IL_(-6) production and the levels of soluble IL_(-2)R (SIL_(-2R)) were studied in PHA stimulated peripheral blood mononuclear cells(PBMC) from 25 patients with esophageal carcinoma and in 31 healthy controls.Furthermore,the levels of serum SIL_(-2R) were determined.The result showed that the ability of IL_(-6) production was significantly elevated in patients (P<0.001),the levels of serum SIL_(-2R) were significantly elevated compared with healthy control (P<0.001).In contrast,no significantly difference was found in the SIL_(-2R) levels of supernatants of cell cultures in vitro (P> 0.05). |
| Keywords: | esophageal carcinoma SIL_2 receptor interleukin_6 |
| 本文献已被 CNKI 等数据库收录！ | |