| 艾叶挥发油提取工艺的优化 |
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| 引用本文： | 赵志鸿,;耿楠,;黄勇勇,;吴芳,;李锦玉,;王桂芳,;张壮丽,;张小俊.艾叶挥发油提取工艺的优化[J].中国医药导报,2014(35):66-69. |
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| 作者姓名： | 赵志鸿 ;耿楠 ;黄勇勇 ;吴芳 ;李锦玉 ;王桂芳 ;张壮丽 ;张小俊 |
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| 作者单位： | [1]郑州大学医药科学研究院,河南郑州450052; [2]河南省肝病药理重点实验室,河南郑州450052; [3]郑州大学药学院,河南郑州450001; [4]郑州大学临床医学系,河南郑州450001 |
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| 基金项目： | 河南省重点科技攻关计划项目（编号122102310651）. |
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| 摘 要： | 目的：通过正交试验法优化艾叶挥发油提取工艺。方法采用正交试验法考察工艺，其中考察因素为提取时间（A）、料液比（B）和浸泡时间（C），每个因素取3个水平，以得油率为考察指标对艾叶挥发油的提取工艺进行优选。结果艾叶挥发油最佳提取条件为料液比1：10、浸泡4 h、提取3 h，平均得油率为0.416%，RSD=2.64%（n=3）。结论优选的提取工艺得油率较高，工艺稳定可行，可为实际生产提供依据。
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| 关 键 词： | 艾叶 挥发油 提取工艺 正交试验法 |
Study on the optimum extraction processes of essential oil of Folium Artemisi-ae argyi |
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| Institution: | ZHAO Zhihong, GENG Nan, HUANG Yongyong, WU Fang, LI Jinyu, WANG Guifang, ZHANG Zhuangli, ZHANG Xiaojun (1.Academy of Medical and Pharmaceutical Sciences, Zhengzhou University, He＇nan Province, Zhengzhou 450052, China; 2.Key Lab of Hepatic Pharma. of He＇nan, He＇nan Province, Zhengzhou 450052, China; 3.School of Pharmacy, Zhengzhou University, He＇nan Province, Zhengzhou 450001, China; 4.Division of Clinical Medicine, Zhengzhou University, He＇nan Province, Zhengzhou 450051, China) |
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| Abstract: | Objective To optimize the best extracting process of essential oil of Folium A rtemisiae argyi. Methods The orthogonal test was applied. The following factors with three levels were considered：extracting time （A）, the proportion of material to solvent （B）, and soaking time （C）. Extracting yield was investigated as the evaluation indicators. Results The best extracting process was obtained at the following conditions：ratio of solid to liquid of 1：10, soaking time of 4 h, extraction time of 3 h. The average oil production rate was 0.416%, RSD=2.64%（n = 3）. Conclusion The preferred process has higher oil yield, it is stable, feasible, and can provide basis for actual production. |
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| Keywords: | Folium Artemisiae argyi Essential oil Extracting process Orthogonal test |
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