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人乳头瘤病毒预防性疫苗的研究进展
引用本文:阿荣其其格,段仙芝,尼玛. 人乳头瘤病毒预防性疫苗的研究进展[J]. 内蒙古医学杂志, 2012, 44(7): 828-831
作者姓名:阿荣其其格  段仙芝  尼玛
作者单位:1. 内蒙古民族大学,内蒙古通辽,028000
2. 北京首都医科大学附属同仁医院妇产科,北京,100730
3. 赤峰市阿旗罕苏木卫生院,内蒙古赤峰,025559
摘    要:
20世纪80年代初德国病毒学家Harald Zur Hausen首次提出人乳头瘤病毒(Human papillomavirus)感染与宫颈癌密切相关的假设,此后国内外大量的证据使得人们对子宫颈癌和HPV的因果关联达成了共识,即HPV感染是子宫颈癌的必然病因。这一发现不但促进了基于HPVDNA检测子宫颈癌新筛查技术的发展,同时也研发成功第一种癌症预防性疫苗,即HPV预防性宫颈癌疫苗。

关 键 词:人乳头瘤病毒  宫颈癌  疫苗

Human Papilloma Virus Prophylactic Vaccine Research Progress
Arongqiqige , DUAN Xian-Zhi , NI Ma. Human Papilloma Virus Prophylactic Vaccine Research Progress[J]. Inner Mongolia Medical Journal, 2012, 44(7): 828-831
Authors:Arongqiqige    DUAN Xian-Zhi    NI Ma
Affiliation:1.Department of Postgraduate 2010,National University of Inner Mongolia,Inner Mongolia Tongliao 028000 China;2.Department of Gynaecology and Obstetrics,The Affiliated Tongren Hospital,Beijing Capital University of Medical Sciences,Beijing 100730 China;3.The Public Aqihansumu Health Centre of Inner Mongolia Chifeng City,Chifeng 025559 China)
Abstract:
Objective:In 1980s,Germany virologist——Harald Zur Hausen firstly raise the hypotheses that human papilloma virus(HPV) infection closely related to cervical cancer.Afterwards,lots of evidence proved the causal relationship between persistent HPV infection and cervical cancer,and made a conclusion that HPV infection is the necessary cause of cervical cancer.This discovery is marked as a milestone in cervical cancer prevention,which not only promotes the development of HPV DNA-based cervical cancer screening technology,but also guides the development of HPV prophylactic vaccine for cervical cancer.This review states the latest researches of HPV vaccine.
Keywords:Human papilloma virus  Cervical cancer  Vaccine
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