| 高山红景天提取物的药理研究 |
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| 引用本文： | 袁文学,高淑范,栗砚芬,邢春生,卢希贤,郑俊民,王志清. 高山红景天提取物的药理研究[J]. 沈阳药科大学学报, 1986, 0(3) |
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| 作者姓名： | 袁文学 高淑范 栗砚芬 邢春生 卢希贤 郑俊民 王志清 |
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| 作者单位： | 辽宁省药物研究所，辽宁省药物研究所，辽宁省药物研究所，辽宁省药物研究所，沈阳药学院，沈阳药学院，沈阳药学院 |
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| 摘 要： | 红景天提取物皮下注射100mg/kg,一次给药或连续三天给药均有抗游泳疲劳作用,100mg/kg一次给药具有抗抓棒疲劳作用,100—200mg/kg 均无增强或拮抗戊巴比妥钠催眠作用,90mg/kg 无抗常压缺氧作用,45—200mg/kg一次或多次给药均无抗低压缺氧作用,10mg/kg 无抗肾上腺素高血糖作用。红景天浸膏灌胃给药1.25—10.0g/kg 一次给药,或5g/kg 连续六天给药均无抗抓棒疲劳作用。红景天提取物给小鼠灌胃给药 LD_(50)为45.01±7.37g/kg,给小鼠腹腔注射 LD_(50)为2.68±0.67g/kg。
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| 关 键 词： | 高山红景天 抗疲劳 催眠 缺氧 高血糖 半数致死量 |
STUDIES ON THE PHARMACOLOGICAL ACTIONS OF EXTRACTS OF RHODIOLA SACHALINENSIS |
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| Yuan Wenxue Gao Shufan Li Yanfen Xing Chunsheng Liaoning Institute of Materia MedicaLu Xixian Zheng Junmin Wang Zhiqing Shenyang College of Pharmacy. STUDIES ON THE PHARMACOLOGICAL ACTIONS OF EXTRACTS OF RHODIOLA SACHALINENSIS[J]. Journal of Shenyang Pharmaceutical University, 1986, 0(3) |
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| Authors: | Yuan Wenxue Gao Shufan Li Yanfen Xing Chunsheng Liaoning Institute of Materia MedicaLu Xixian Zheng Junmin Wang Zhiqing Shenyang College of Pharmacy |
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| Affiliation: | Yuan Wenxue Gao Shufan Li Yanfen Xing Chunsheng Liaoning Institute of Materia MedicaLu Xixian Zheng Junmin Wang Zhiqing Shenyang College of Pharmacy |
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| Abstract: | Extracts of Rhodiola Sachalinensis(ERS)sc 100mg/kg once daily for 1 day or 3 days produced antifatigue in mice swimming or catching rod.ERS sc 100- 200mg/kg had no effect on the pentobarbital-induced hypnosis;45-200mg/kg once daily for 1 day or several days did not affect hypoxia in mice;10mg/kg showed no effect on adrenaline-induced hyperglycemia. |
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| Keywords: | Rhodiola Schalinensis Antifatigue Hypnosis Hypoxia Hyperglycemia LD_(50) |
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