Comparison of Infasurf (calf lung surfactant extract) to Survanta (Beractant) in the treatment and prevention of respiratory distress syndrome期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Comparison of Infasurf (calf lung surfactant extract) to Survanta (Beractant) in the treatment and prevention of respiratory distress syndrome

Authors:	BT Bloom J Kattwinkel RT Hall PM Delmore EA Egan JR Trout MH Malloy DR Brown IR Holzman CH Coghill WA Carlo AK Pramanik MA McCaffree PL Toubas S Laudert LL Gratny KB Weatherstone JH Seguin LD Willett GR Gutcher DH Mueller WH Topper

Affiliation:	Columbia Wesley Medical Center and University of Kansas School of Medicine-Wichita, Wichita, Kansas 67214, USA.

Abstract:	OBJECTIVE: To compare the relative safety and efficacy of Infasurf (calf lung surfactant extract; ONY, Inc, Amherst, NY, IND #27169) versus Survanta (Beractant, Ross Laboratories, Columbus, OH) in reducing the acute severity of respiratory distress syndrome (RDS) when given at birth and to infants with established RDS. DESIGN: A prospective, randomized, double-blind, multicenter clinical trial. SETTING: Thirteen neonatal intensive care units participated in the treatment arm: seven of these concurrently participated in the prevention arm. PATIENTS: The treatment arm enrolled infants of

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