血清唾液酸检测在大肠癌中的临床意义

目的了解血清唾液酸在大肠癌中的临床意义。方法对112例大肠癌患者，48例非癌症疾患者，72例正常对照组人员的血清唾液酸进行检测。结果上述三组唾液酸含量分别为：（727．4±71．8）mg／L、（441．0±49．1）mg／L、（437．0±46．2）mg／L；其阳性率分别为：81．25％、4．16％、O％大肠癌组唾液酸含量与阳性率均显著高于非癌症疾患组与正常对照组（P〈0．01），而后两者之间无差异性（P〉0．05）。结论血清唾液酸是一个重要的大肠癌血清学标记物，可作为大肠癌的手术效果与疗效监测的观察指标之一。

The clinic value of serum salivary acid test for large intestine cancer

Objective To understand the clinic meaning of serum salivary acid in large intestine cancer. Methods Test the blood serum salivary of 112 cases of large intestine cancer patients,48 cases of patients who are not suffering cancer, 72 normal people for contrast. Results The separate containing amounts of the sal- ivary acids are ： （ 727. 4 ± 71.8 ） rag/L, （441.0± 49. 1 ） mg/L, （437. 0 ± 46. 2） mg/L; the separate positive rates are 81.25% ,4. 16% ,0%. The content of the salivary acid and the positive rates of the large intestine cancer patients are all obviously higher than those of the un-cancer group and normal contrast group （ P 〈 0. 01 ）, but the later two groups have no difference （P 〉 0. 05）. Conclusions Serum salivary acid can be seen as the observa- tion index for the large intestine cancer operation effect and curative effect, and has important clinic diagnostic value for large intestine cancer.