早期干预钙磷代谢对慢性肾脏病左室肥厚的影响

目的 探讨早期干预钙磷代谢对改善慢性肾脏病患者左室肥厚的影响.方法 将住院治疗的116例非透析慢性肾脏病3、4期患者随机分为干预组和对照组,对干预组患者进行早期钙磷代谢干预,观察两组患者的血钙、血磷和左室心肌质量指数的变化情况.结果 干预组患者干预后的血磷、钙磷乘积、血全段甲状旁腺素均显著低于对照组,差异有统计学意义（P＜0.05）;干预组的LVMI显著低于干预前,也显著低于对照组,差异有统计学意义（P＜0.05）.结论 对慢性肾脏病患者进行早期钙磷代谢干预能有效改善患者的左室肥厚症状,有利于患者整个病情的改善.

Influence of early intervention in calcium and phosphorus metabolism in chronic kidney disease left ventricular hypertrophy

Objective To investigate the early intervention to improve calcium and phosphorus metabolism in chronic kidney disease patients left ventricular hypertrophy. Methods 116 cases of non-dialysis patients with chronic kidney disease were randomly divided into 3,4-intervention group and control group, intervention group patients with calcium and phosphorus metabolism in early intervention were observed in patients with calcium, phosphorus, and left ventricular mass index changes. Results Patients in the intervention group after the intervention of phosphorus,calcium and phosphorus product,serum parathyroid hormone were significantly lower than the control group,the difference was all statistically significant (all P＜0.05 );intervention group of LVMI was significantly lower than before the intervention, but also significantly lower than the control group, the difference was statistically significant (P＜0.05). Conclusion Patients with chronic renal calcium and phosphorus metabolism of early intervention can improve symptoms in patients with left ventricular hypertrophy is beneficial to the improvement of patients with the disease.