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| 垂体肿瘤转化基因的研究进展 | |
| 引用本文： | 石祥呈,康凯夫. 垂体肿瘤转化基因的研究进展[J]. 国际病理科学与临床杂志, 2008, 28(1): 16-71 |
| 作者姓名： | 石祥呈 康凯夫 |
| 作者单位： | 广东医学院病理学系,广东,湛江,524023;广东省佛山市顺德第一人民医院病理科,广东,佛山,528300 |
| 摘 要： | 垂体肿瘤转化基因(PTTG) 是一个新近从垂体瘤组织中分离到的原癌基因。目前研究发现PTTG在许多肿瘤组织内高表达, 是一种强肿瘤转化基因,可通过多种机制参与肿瘤的发生发展,并受多种因子的调控，对体外细胞转化及体内肿瘤形成有重要作用。 |
| 关 键 词： | 垂体肿瘤转化基因 肿瘤 转化 |
| 文章编号： | 1673-2588(2008)01-0068-04 |
| 收稿时间： | 2007-07-05 |
| 修稿时间： | 2007-07-05 |
Progression of pituitary tumor-transforming gene |
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| SHI Xiang-cheng,KANG Kai-fu. Progression of pituitary tumor-transforming gene[J]. Journal of International Pathology and Clinical Medicine, 2008, 28(1): 16-71 | |
| Authors: | SHI Xiang-cheng KANG Kai-fu |
| Affiliation: | 1. Department of Pathology,Guangdong Medical College，Zhanjiang Guangdong 524023, 2. Department of Pathology,First People's Hospital of Shunde,Foshan Guangdong 528300,China |
| Abstract: | Pituitary tumor-transforming gene (PTTG) is a proto-oncogene separated from pituitary tumor tissue recently.PTTG is overexpressed in many tumors and is a strong tumor transforming gene. PTTG plays a role in tumor development and progression through various mechanisms and is regulated by several factors. PTTG is a key factor in cell transformation in vitro and tumor formation in vivo. |
| Keywords: | pituitary tumor-transforming gene tumor transformation |
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