老年肺癌141例临床分析

目的探讨老年肺癌患者的临床特点。方法收集经病理明确诊断的老年肺癌患者临床资料,回顾性分析患者年龄、性别、ECOG评分、临床症状、病理类型、临床分期、转移部位、合并症等。结果 141例老年肺癌患者平均年龄74.48岁,男女性别比例为4.64∶1,ECOG评分0~1分患者占89.36%;主要症状为咳嗽(66.7%)、胸闷(17.7%)、疼痛(17.7%),61%患者为非小细胞肺癌(NSCLC),T1患者仅5.67%,N2-3患者达78.72%,Ⅲ~Ⅳ期患者高达90%以上。肺、胸膜转移最为常见,而远处转移(M1b)多见于骨、脑、肝脏、肾上腺。合并疾病患者达52.5%。结论老年肺癌患者临床表现无特异性且合并疾病较多,临床分期较晚,但行为状态较好,值得临床进一步关注其早期诊断、治疗及预后。

Clinical analysis of 141 cases of elderly patients with lung cancer

Objective To investigate the clinical characteristics of elderly patients with lung cancer. Meth-ods The clinical data of 141 cases diagnosed with lung cancer by pathology or cytology were analyzed, including their age, gender, Eastern Cooperative Oncology Group performance status(ECOG PS), symptom, pathology type, TNM stage, metastatic sites and complications. Results The average age was 74. 48, and the ratio of male to female was 4. 64. 89. 36% of the patients showed 0-1 in ECOG status performance, and the common symptoms were cough(66. 7%), chest distress(17. 7%)and pain(17. 7%). 61% of the patients were non small cell lung cancer. In regard to TNM stage, only 5. 67% showed T1, but 78. 72% with N2 -3 and more than 90% with stage Ⅲ~Ⅳ. Lung and pleura were the most frequent metastatic sites, followed by bone, brain, liver and adrenal gland. 52. 5% of the patients had complications. Conclusion Elderly patients with lung cancer have no specific clinical symptoms, but they have much more complications and advanced stages. Their performance status is good, thus, further study should focus on its early diagnosis, treatment and prognosis.