匹多莫德辅助治疗儿童慢性扁桃体炎急性发作疗效观察

目的观察匹多莫德在儿童慢性扁桃体炎急性发作治疗中的临床疗效~([1])。方法于2011年3月至2012年3月门诊或住院诊断慢性扁桃体炎急性发作资料完整的5~12岁患儿中,随机选取应用匹多莫德口服液的42例为观察组;未应用的48例为对照组。两组均采用常规抗感染、对症支持等治疗,观察组在常规治疗基础上加用匹多莫德口服液治疗。比较两组治疗的总有效率、症状、体征变化时间及随访治疗1年后急性发作次数,再住院率等。结果观察组总有效率为95.23%,对照组总有效率为75.0%,两组比较P0.05;观察组发热、扁桃体肿大消退时间均短于对照组;再次急性发作及因扁桃体炎再次就诊次数明显少于对照组。结论在儿童慢性扁桃体炎急性发作治疗过程中加用匹多莫德治疗后,临床取得显著效果,值得推广应用。

Effect of pidotimod in the treatment of children with acute attack chronic tonsillitis

Objective To observe the clinical effect of pidotimod in the treatment of children with acute at-tack chronic tonsillitis. Methods From March 2011 to March 2012, the study selected 42 children with chronic tonsillitis given pidotimod as the observation group and 48 cases as the control group. All children were given conven-tional anti-infection and symptomatic treatment. The total effective rate, symptoms, signs, and frequency of acute at-tack during the 1-year follow-up were compared. Results The total effective rate of the observation group was 95. 23%, and 75% in the control group (P<0. 05). The fever disappeared time and tonsils fade time were shorter in the observation group than in the control group. The incidence of acute attack and tonsillitis were lower in the ob-servation group than in the control group. Conclusion Pidotimod has certain curative effect in the treatment of chil-dren with acute attack chronic tonsillitis.