SARS临床特点分析

目的 :探讨SARS的临床特点、诊治方法。方法 :对 2 0 0 3年 3月至 2 0 0 3年 5月收治的 2 9例传染性非典型肺炎患者进行回顾性分析 ,总结其流行病学特点、临床表现、血常规及影像学检查特点。结果 :本组 2 9例全部以发热为首发症状 ,有明确接触史者 2 5例 (占 86 .2 % ) ,第一次血常规白细胞降低者有 8例 (占 2 7.6 % ) ,淋巴细胞计数 <0 .9× 10 9 L者 19例 (占 6 5 .5 % ) ,白细胞计数出现进行性下降者 2 2例 (占 75 .9% )。所有患者胸片显示肺部阴影 ,其中迅速进展者 18例 (占 6 2 .1% )。治疗采用抗病毒、抗感染、支持等综合治疗 ,重症患者使用大剂量甲泼尼龙和无创机械通气。结论 :流行病学史、临床特点是早期诊断的关键 ,治疗采取综合方法 ,对重症患者使用大剂量激素、无创机械通气治疗有效

Clinical analysis of 29 cases of SARS

Objective: To investigate clinical features and treatment of severe acute respiratory syndrome (SARS). Methods:29 cases of SARS patients' clinical data were analyzed retrospectively. Results:All the 29 cases had fever at the early stage of the disease. 25 cases had close contact with other SARS patients before their fever. Eight cases had leucopenia, and 22 had progressing leukocyte decreasing. All patients' chest radiographs showed large area of interstitial infiltrates or shadows. 29 patients received antibiotics and anti-virus drugs treatments. Severe SARS patients received methylprenisolone and non-invasive mechanical ventilation. Results:Both epidemiologic history and clinical findings are the major evidences for clinical diagnosis of SARS. Large dose of adrenal steroid and mechanical ventilation may be valuable for severe SARS patients.