首页 | 本学科首页   官方微博 | 高级检索  
     


The etiology of adolescent idiopathic scoliosis
Authors:Ahn Uri Michael  Ahn Nicholas U  Nallamshetty Leelakrishna  Buchowski Jacob M  Rose Peter S  Miller Nancy H  Kostuik John P  Sponseller Paul D
Affiliation:New Hampshire Spine Institute, Bedford, USA.
Abstract:The etiology of adolescent idiopathic scoliosis (AIS), the most common form of scoliosis, is unclear. Researchers with divergent perspectives have tried to better define this etiology. Genetics, growth hormone secretion, connective tissue structure, muscle structure, vestibular dysfunction, melatonin secretion, and platelet microstructure are major areas of focus. In this article, we review the literature in these areas and present the consensus on proposed hypotheses. Studies that simplify the etiology to a single factor have been inconclusive or unsuccessful. Most likely, the etiology is multifactorial, and reported associations are links in pathogenesis rather than etiologic factors. Research is needed to better define the role of all factors in AIS development.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号