| 动态浊度法测定间苯三酚注射液中细菌内毒素含量 |
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| 引用本文： | 吕海华,李敏. 动态浊度法测定间苯三酚注射液中细菌内毒素含量[J]. 中国药业, 2008, 17(1): 19-20 |
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| 作者姓名： | 吕海华 李敏 |
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| 作者单位： | 浙江省宁波市药品检验所,浙江,宁波,315040 |
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| 摘 要： | 目的探讨间苯三酚注射液的细菌内毒素定量分析法。方法采用2005年版《中国药典（二部）》中的动态浊度法。结果供试品稀释50倍可以排除干扰，回收率在50％～200％范围内，试验结果与家兔升温法的一致。结论用动态文度法测定闯苯三酚注射液的细菌内毒素含量准确有效。
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| 关 键 词： | 动态浊度法 间苯三酚注射液 内毒素 干扰试验 |
| 文章编号： | 1006-4931(2008)01-0019-02 |
| 修稿时间： | 2007-03-02 |
Bacterial Endotoxin Test for Phloroglucinol Injection by Dynamic Turbidimetric Assay |
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| Lu Haihua,Li Min. Bacterial Endotoxin Test for Phloroglucinol Injection by Dynamic Turbidimetric Assay[J]. China Pharmaceuticals, 2008, 17(1): 19-20 |
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| Authors: | Lu Haihua Li Min |
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| Affiliation: | (Ningbo Institute for Drug Control, Ningbo, Zhefiang, China 315040) |
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| Abstract: | Objective To study the interference of Phloroglucinol Injection in bacterial endotoxin test and to establish the assay method of bacterial endotoxin by dynamic turbidimetry.Methods Interfering tests for bacterial endotoxin test were used according to China Pharmacopoeia(edition 2005).Results 1:50 solution of Phloroglucinol Injection showed no inference in the test,and the endotoxin recovery rate was more than 50%and less than 200%.Conclusion Dynamic turbidimetric assay method can be used accurately and effectively to determine quantitively bacterial endotoxin for Phloroglucinol Injection. |
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| Keywords: | dynamic turbidimetric assay Phloroglucinol Injection bacterial endotoxin interfering test |
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