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Deletion of atrophy enhancing genes fails to ameliorate the phenotype in a mouse model of spinal muscular atrophy
Affiliation:1. University Orthopaedics, Hand and Reconstructive Microsurgery (UOHC), National University Health System, 1E Kent Ridge Rd, NUHS Tower Block Level 11, 119228 Singapore;2. Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 11, Singapore 119228, Singapore;1. Discipline of Physiology, School of Medical Sciences, Bosch Institute, University of Sydney, Camperdown, Australia;2. Discipline of Anatomy & Histology, School of Medical Sciences, Bosch Institute, University of Sydney, Camperdown, Australia
Abstract:
Keywords:Spinal muscular atrophy (SMA)  Muscle ubiquitin ligases  Muscle atrophy F-box  MAFbx (Atrogin1)  Muscle RING Finger 1  MuRF1 (Trim63)
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