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| 玻璃体切割术治疗独眼视网膜母细胞瘤局灶性玻璃体种植灶 | |
| 引用本文： | 季迅达,陆上麟,赵培泉. 玻璃体切割术治疗独眼视网膜母细胞瘤局灶性玻璃体种植灶[J]. 中华医学杂志(英文版), 2013, 126(13): 2589-2590 |
| 作者姓名： | 季迅达 陆上麟 赵培泉 |
| 作者单位： | 上海交通大学医学院附属新华医院,上海交通大学医学院附属新华医院,上海交通大学医学院附属新华医院 |
| 基金项目： | This,study,was,supported,by,a,grant,from,Innovation,Program,of,Shanghai,Municipal,Education,Commission(项目编号：12YZ048) |
| 摘 要： | Vitreous seeds of retinoblastoma are one of the main reasons for treatment failure using globe-conserving therapy due to their poor response to therapy.This is most likely secondary to the difficulty for chemotherapeutic drugs to permeate into the vitreous cavity due to the bloodeye barrier) Currently,laser coagulation or cryotherapy is not used for vitreous seeds.External beam radiotherapy has been seldom used for vitreous seeds due to radiationrelated complications.2 Recently,several reports have showed repeated intravitreal injections of anticancer drugs,such as melphalan,may be an option for vitreous seeds.3 However,long-term efficacy of this approach is unsure and this treatment is unavailable at many treatment centers.Furthermore,repeated intravitreal injections entail an increased risk of extraocular dissemination of tumor cells. |
| 关 键 词： | 种子数量 切割技术 冷冻治疗 玻璃体 视网膜 母细胞 肿瘤细胞 手术过程 |
| 收稿时间： | 2013-02-08 |
| 修稿时间： | 2013-07-05 |
Vitrectomy for localized vitreous seeds of retinoblastoma in an only eye |
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| JI Xun-d,LU Shang-lin and ZHAO Pei-quan. Vitrectomy for localized vitreous seeds of retinoblastoma in an only eye[J]. Chinese medical journal, 2013, 126(13): 2589-2590 | |
| Authors: | JI Xun-d LU Shang-lin ZHAO Pei-quan |
| Affiliation: | Department of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China |
| Abstract: | Vitreous seeds of retinoblastoma are one of the main reasons for treatment failure using globe-conserving therapy due to their poor response to therapy.This is most likely secondary to the difficulty for chemotherapeutic drugs to permeate into the vitreous cavity due to the bloodeye barrier) Currently,laser coagulation or cryotherapy is not used for vitreous seeds.External beam radiotherapy has been seldom used for vitreous seeds due to radiationrelated complications.2 Recently,several reports have showed repeated intravitreal injections of anticancer drugs,such as melphalan,may be an option for vitreous seeds.3 However,long-term efficacy of this approach is unsure and this treatment is unavailable at many treatment centers.Furthermore,repeated intravitreal injections entail an increased risk of extraocular dissemination of tumor cells. |
| Keywords: | retinoblastomaitreous seeds vitrectomy |
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