海南百岁老人血清白蛋白水平与健康相关生活质量的关联性研究

目的:探讨中国海南百岁老人血清白蛋白水平与健康相关生活质量的关系。方法:本研究数据来自中国海南百岁老人队列研究2014-2016年横断面数据集，共纳入1 002名百岁老人进行问卷调查、体格检查和生物学标本检测。采用EQ-5D-VAS量表测量健康相关生活质量，采用多重线性回归和多元logistic回归分析血清白蛋白和健康...

Association between serum albumin level and health-related quality of life in Hainan centenarians: a cross-sectional study

Objective To investigate the association between serum albumin levels and health-related quality of life in centenarians in Hainan province,China.Methods We conducted a full sample centenarian cohort study in a community population in Hainan from 2014 to 2016,which included 1002 centenarians for questionnaire surveys,physical examinations and biological tests.The EQ-5D-VAS scale was used to evaluate health-related quality of life,and multiple linear regression and multiple logistic regression analyses were used to analyze the association between serum albumin levels and health-related quality of life.Results There was a positive linear relationship between serum albumin levels and EQ-5D/VAS score.The normalizedβvalues in the fully adjusted model was 0.156(P<0.001).In the multivariate logistic regression analysis,after fully adjusting the covariates,the risk of health related life quality impairment in the lower albumin group was 2.369 times(95%CI:1.424-3.939)than that in the higher albumin group.Gender stratified analyses showed that the OR was 4.406(95%CI:1.537-12.631)in male centenarians and 2.035(95%CI:1.125-3.680)in female centenarians.Conclusion Lower serum albumin level was associated with impaired health-related quality of life in centenarians in Hainan.