妊娠合并急性胰腺炎的研究新进展

妊娠合并急性胰腺炎严重威胁母婴健康,在病因、诊断和治疗上存在特殊性。其病因主要是妊娠期体内内分泌的变化及妊娠本身机械作用对机体的影响更易诱发胆管系统疾病和妊娠期高脂血症并有脂蛋白脂酶活性的变化等。黏附分子和巨噬细胞移动抑制因子参与了其发病的分子机制。超声、超声内镜和磁共振胰胆管造影术对诊断具有重要作用。腹腔镜胆囊切除术、内镜逆行胰胆管造影术联合Oddi括约肌切开术成为手术治疗的新选择。

Current Progress in Research on the Acute Pancreatitis in Pregnancy

Acute pancreatitis in pregnancy, a serious threat to maternal and child health, has particularity in the etiology, diagnosis and treatment. Endocrine changes during pregnancy and mechanical influence of pregnancy on the body may easily induce biliary system disorders, hyperlipidemia and activity changes of hpopretein lipase. Adhesion molecules and macrophage migration inhibitory factor are involved in the molecular mechanism of pathogenesis. Ultrasound, endoscopic ultrasound and magnetic resonance chalangiopancreatography play an important role in the diagnosis. Laparoscopic cholecystectomy, endoscopic retrograde cholangiopancreatography combined Oddi sphineterotomy become a new choice of surgical treatment.