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Evidence of C-Cell Destruction in the Thyroid Gland of Mice Exposed to High 131I Doses |
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| Authors: | R. E. Feinstein E. J. Gimeno M. El-Salhy E. Wilander G. Walinder |
| Affiliation: | a Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsalab The Department of Pathology, Akademiska Sjukhuset, University of Uppsala, Uppsalac The Unit of Radiologic Oncology, University of Stockholm, Stockholm, Sweden |
| Abstract: | The parafollicular cells of the thyroid gland were visualized by means of the Sevier-Munger silver technique in normal mice and in mice receiving 131I in amounts sufficient to completely destroy the thyroid tissue. The destruction of the C-cells was observed in all 131I injected mice, and no histologic signs of recovery were seen during a period of 40 days following the treatment. |
| Keywords: | Radiobiology 131I thyroid C-cell destruction |
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