降钙素原与感染性疾病的临床研究进展

降钙素原(PCT)对早期细菌感染性疾病诊断有明确的临床价值,PCT可用于鉴别细菌与非细菌感染,对于严重细菌感染性疾病的诊断较C反应蛋白(CRP)特异,对临床诊治具有指导意义。血清PCT是鉴别细菌性感染引发脓毒血症快捷、敏感、准确的监测手段。细菌感染性疾病患者可在PCT指导下安全使用抗生素,能够降低抗生素使用率和抗生素的使用时间,避免过度使用抗生素。PCT水平对疗效判断及预测预后有重要的参考意义。

Clinical Research Progress of Procalciton and Infectious Diseases

Procalcitonin（PCT） has definite clinical value in early diagnosing bacterial infectious disea- ses,which can be used to differentiate bacterial infection from non-bacterial infection. PCT is more specific than CRP for serious bacterial infections diagnosis, which has guiding significance for clinical diagnosis and treatment. PCT is a speedy, sensitive, precise inspecting method which is used to detect sepsis caused by bac- terial infection. PCT could be used safely as guidance of antibiotics employment for the treatment of patients with bacterial diseases, leading to decrease the duration and frequency of antibiotic usage, to reduce the unnecessary antibiotic exposure. The level of serum PCT has an important reference value in judging the ther- apeutic effect and predicting the prognosis.