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| 蝎毒素对小鼠多种免疫细胞活化的影响 | |
| 引用本文： | 张文选,江华,白洁,马杰,李丹,刘文第. 蝎毒素对小鼠多种免疫细胞活化的影响[J]. 郑州大学学报(医学版), 2011, 46(1): 51-53 |
| 作者姓名： | 张文选 江华 白洁 马杰 李丹 刘文第 |
| 作者单位： | 1. 河南职工医学院继续教育部,郑州,451191;河南中医学院基础医学院生化学科,郑州,450008 2. 河南中医学院基础医学院生化学科,郑州,450008 3. 郑州大学附属肿瘤医院病理科,河南省肿瘤医院病理科,郑州,450003 |
| 基金项目： | 河南省科技攻关计划基金资助项目0623030800; 河南省医学科技创新人才工程基金资助项目20060142 |
| 摘 要： | 目的:探讨东亚钳蝎毒素(BMK IA)对小鼠体内多种免疫细胞活化的影响.方法:C57BL/6小鼠48只,随机数字表法分为空白对照组和实验组,每组分为4批,每批6只,各检测一种免疫细胞.实验组小鼠一次性静脉注射0.004 mg/kg的BMK IA,对照组给予等体积的生理盐水.流式细胞术分别检测2组小鼠给药0、2、8、12... |
| 关 键 词： | 蝎毒素 免疫细胞 CD69 小鼠 |
Effects of buthus martensii karsch immune active on activation of immunocytes in mice |
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| ZHANG Wenxuan , JIANG Hua , BAI Jie , MA Jie , LI Dan , LIU Wendi. Effects of buthus martensii karsch immune active on activation of immunocytes in mice[J]. Journal of Zhengzhou University: Med Sci, 2011, 46(1): 51-53 | |
| Authors: | ZHANG Wenxuan JIANG Hua BAI Jie MA Jie LI Dan LIU Wendi |
| Affiliation: | ZHANG Wenxuan1,2),JIANG Hua2),BAI Jie2),MA Jie3),LI Dan2),LIU Wendi2)1)Department of Continuing Education,Henan Employee Medical College,Zhengzhou 451191 2)Biochemistry Discipine,School of Basic Medicine,Henan University,Traditional Chinese Medicine,Zhengzhou 450008 3)Department of Pathology,Tumor Hospital,Zhengzhou University,Department of Pathology,Henan Tumor Hospital,Zhengzhou 450003 |
| Abstract: | Aim:To investigate the effects of buthus martensii karsch immune active(BMK IA)on activation of multiple immunocytes in mice.Methods:A total of 48 C57BL/6 mice were allocated into experimental group and control group.The mice in experimental group were injected intravenously with a single dose of BMK IA(0.004 mg/kg),and those in control group were given normal saline.The expression of cell-specific antigens and CD69 in peripheral monocytes,NK cells,B cells,CD4+T and CD8+T cells were assessed using immunoflu... |
| Keywords: | buthus martensii karsch immune active immunocyte CD69 mouse |
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