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The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis
Authors:Gozde Yildirim Cetin  Eda Ganiyusufoglu  Dilek Solmaz  Yonca Cagatay  Sibel Yılmaz Oner  Burak Erer
Affiliation:1. Division of Rheumatology, Department of Internal Medicine and gozdeyildirimcetin@gmail.com;3. Department of Biochemistry Research Laboratory, School of Medicine, Sutcu Imam University, Kahramanmaras, Turkey,;4. Department of Internal Medicine, Division of Rheumatology, Dokuz Eylul University School of Medicine, Izm?r, Turkey,;5. Department of Internal Medicine, Division of Rheumatology, B?l?m University School of Medicine, Istanbul, Turkey,;6. Department of Internal Medicine, Division of Rheumatology, Marmara University School of Medicine, Istanbul, Turkey,;7. Department of Internal Medicine, Division of Rheumatology, Istanbul University School of Medicine, Istanbul, Turkey,
Abstract:
A relationship between the presence of amyloidosis and SAA1 genotype has been shown in recent studies of (principally) familial Mediterranean fever patients. We found that the SAA1 rs12218 polymorphism was significantly more prevalent in ankylosing spondylitis patients with amyloidosis.
Keywords:Amyloidosis  ankylosing spondylitis  type 1/type 2 serum amyloid A protein genes
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