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Visualization of the thymus with therapeutic doses of radioiodine in patients with thyroid cancer
Authors:Takatoshi Michigishi  Yuji Mizukami  Noriyuki Shuke  Kunihiko Yokoyama  Masakuni Noguchi  You Watanabe  Osamu Matsui  Tamio Aburano  Norihisa Tonami  Kinichi Hisada
Affiliation:(1) Department of Nuclear Medicine, Kanazawa University Hospital, 13-1, Takara-machi, 920 Kanazawa, Japan;(2) Pathology Section, Kanazawa University Hospital, 13-1, Takara-machi, 920 Kanazawa, Japan;(3) Department of Surgery (II), Kanazawa University Hospital, 13-1, Takara-machi, 920 Kanazawa, Japan;(4) Department of Surgery (I), Kanazawa University Hospital, 13-1, Takara-machi, 920 Kanazawa, Japan;(5) Department of Radiology, Kanazawa University Hospital, 13-1, Takara-machi, 920 Kanazawa, Japan
Abstract:
Two cases of papillary carcinoma of the thyroid are presented in which whole-body scans following therapeutic doses of iodine-131 revealed intense anterior mediastinal uptake. In both cases, the mediastinal uptake was absent from scans obtained after removal of the entire thymus. Histologically, the resected thymus glands showed hyperplasia and contained neither thyroid tissue nor metastatic foci of thyroid carcinoma. We therefore concluded that anterior mediastinal uptake of radioiodine may be caused by hyperplasia of the thymus.
Keywords:Thymus  Thyroid carcinoma  Iodine-131 treatment
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