广州地区体检人群维生素D水平分析

目的对广州地区体检人群25羟基维生素D 25(OH)D] 检查结果进行分析，了解各类人群25(OH)D水平状况，辅助诊断因维生素D缺乏引起的相关疾病。 方法使用化学发光法测定2016年1月至2019年1月共9 163例体检者血清25(OH)D水平，分别比较不同性别、年龄人群25(OH)D营养水平。 结果9 163例体检者血清25(OH)D的平均水平为63.89 nmol/L，正常率为26.41%，不足率为46.45%，缺乏率为27.14%。男性25(OH)D总体正常率为29.29%，不足率为47.36%，缺乏率为23.28%；女性25(OH)D总体正常率为23.26%，不足率为45.42%，缺乏率为31.32%。女性群体25(OH)D缺乏率高于男性，差异有统计学意义(P=0.000)。男女体检群体中25(OH)D缺乏率最高的均为20岁~29岁年龄段，分别为28.75%、42.71%。对不同月份维生素D水平进行分析，发现血清25(OH)D水平最高为5月，最低为2月。 结论广州地区人群存在不同程度的25(OH)D缺乏，且女性相比男性有更高的缺乏率。

Analysis of vitamin D level in people taking physical examination in Guangzhou

ObjectiveThe aim of this study was to help diagnose diseases caused by Vitamin D deficiency by analyzing the 25-hydroxyvitamin D 25(OH)D] level in people taking physical examination in Guangzhou. MethodsThe serum 25(OH)D levels were determined by chemiluminescent assayin 9 163 physical examination subjects from January 2016 to January 2019, and 25(OH)D nutritional levels were compared among different genders and age groups. ResultsMean serum 25(OH)D level of 9 163 subjects was 63.89 nmol/L. Subjects with adequate, inadequate and deficient serum 25(OH)D took percentage of 26.41%, 46.45% and 27.14%, respectively. Male subjects with adequate, inadequate and deficient serum 25(OH)D took percentage of 29.29%, 47.36% and 23.28%, respectively. Female subjects with adequate, inadequate and deficient serum 25(OH)D took percentage of 23.26%, 45.42% and 31.32%, respectively. Serum 25(OH)D deficiency in female subjects was higher than that in male subjects. The difference in this study has statistical significance (P=0.000).The highest 25(OH)D deficiency rate in male and female physical examination groups were in the 20~29 age group(28.75% and 42.71%, respectively). Analysis on vitamin D levels in different months indicated that the highest level of serum 25(OH)D appears in May, while the lowest appears in February. ConclusionThere are different levels of 25 (OH) D deficiency in people living Guangzhou, and women have a higher rate of deficiency than men.