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隐球菌脑膜炎并发颅内压增高的诊治进展
引用本文:常健博,吴昊,魏俊吉. 隐球菌脑膜炎并发颅内压增高的诊治进展[J]. 中国医学科学院学报, 2019, 41(1): 111-117. DOI: 10.3881/j.issn.1000-503X.10481
作者姓名:常健博  吴昊  魏俊吉
作者单位:中国医学科学院 北京协和医学院 北京协和医院神经外科,北京 100730
基金项目:国家科技攻关计划(2018YFA0108600)
摘    要:
隐球菌脑膜炎常出现在免疫力低下的患者中,目前已成为全球重要的医疗问题。颅内压增高是其常见的并发症,作为预后不良的主要影响因素,如何监测、治疗此类疾病是临床关注的焦点。由于隐球菌脑膜炎病理生理机制的特点,药物等内科治疗手段难以取得满意的效果,通常需要有创操作的干预。本文总结了隐球菌脑膜炎并发颅内压增高的相关诊治进展。

关 键 词:隐球菌脑膜炎  颅内压增高  脑室腹腔分流术  脑室外引流  
收稿时间:2018-04-19

Advancement in Diagnosis and Treatment of Elevated Intracranial Pressure in Patients with Cryptococcal Meningitis
CHANG Jianbo,WU Hao,WEI Junji. Advancement in Diagnosis and Treatment of Elevated Intracranial Pressure in Patients with Cryptococcal Meningitis[J]. Acta Academiae Medicinae Sinicae, 2019, 41(1): 111-117. DOI: 10.3881/j.issn.1000-503X.10481
Authors:CHANG Jianbo  WU Hao  WEI Junji
Affiliation:Department of Neurosurgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China
Abstract:
Cryptococcal meningitis(CM)is often seen in immunocompromised patients and has become a global health concern. Elevated intracranial pressure(ICP)is a common complication of CM and often leads to poor prognosis. Monitoring and management of ICP is an important task in CM patients. Invasive intervention is often needed for the elevated ICP in CM patients due to the pathophysiological features of this condition. This article review the recent progress in the diagnosis and treatment of elevated ICP in CM patients.
Keywords:cryptococcal meningitis  elevated intracranial pressure  ventriculoperitoneal shunt  external ventricular drainage  
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