纯钛烤瓷冠和钴铬合金烤瓷冠对种植体周围牙周组织的影响

目的探讨纯钛烤瓷冠和钴铬合金烤瓷冠对种植体周围牙周组织的影响。方法97例行上颌前牙区单颗牙种植修复的病人，根据种植体修复材料的不同分为纯钛组（n=51）和钴铬合金组（n=46）。分别在种植体制备前（T₀）和烤瓷冠黏固后1个月（T₁）、3个月（T₂）、6个月（T₃）、12个月（T₄）对牙周指标进行检测，提取种植体周围组织龈沟液，利用ELISA法对龈沟液中丙二醛（MDA）、超氧物歧化酶（SOD）、谷胱甘肽S-转移酶（GST）和白细胞介素6（IL-6）水平进行检测。结果与T₀时相比，2组病人T₂~T₄时牙龈指数（GI）和牙龈龈沟探诊深度（PD）均明显升高（P < 0.01），钴铬合金组T₂~T₄时龈沟液含量增加（P < 0.05），而纯钛组T₁~T₄时龈沟液含量与T₀时差异均无统计学意义（P>0.05），T₂~T₄时纯钛组GI、PD和龈沟液含量均低于钴铬合金组（P < 0.05~P < 0.01）；与T₀时相比，2组T₃~T₄时龈沟液中MDA和IL-6水平均升高，而SOD和GST水平均降低（P < 0.05~P < 0.01）；纯钛组T₃~T₄时龈沟液中IL-6水平均低于钴铬合金组，而GST水平则高于钴铬合金组（P < 0.05~P < 0.01）。结论随着时间推移，纯钛烤瓷冠和钴铬合金烤瓷冠修复后均会对种植体周围牙周组织产生影响，但纯钛烤瓷冠的刺激作用相对弱于钴铬合金烤瓷冠。

Effect of titanium porcelain crown and cobalt-chromium alloy porcelain crown on periodontal tissue around the implant

ObjectiveTo investigate the effects of titanium porcelain crown and cobalt-chromium alloy porcelain crown on periodontal tissue around the implant.MethodsNinety-seven patients treated with single tooth implant restoration in maxillary anterior teeth region were divided into the titanium group(n=51) and cobalt-chromium alloy group(n=48) according to the differences of restorative material.Before preparation of the implant(T₀), after 1 month(T₁), 3 months(T₂), 6 months(T₃) and 12 months(T₄) of porcelain crowns bonding, the periodontal indicators were tested, respectively.The gingival crevicular fluid surrounding implant tissues were extracted from T₀ to T₄, respectively, and the levels of malondialdehyde(MDA), superoxide dismutase(SOD), glutathione S-transferase(GST), and interleukin 6(IL-6) in gingival crevicular fluids were detected.ResultsCompared with T₀, the gingival index(GI) and gingival sulcus exploration depth(PD) in two groups increased(P < 0.01), and the content of gingival crevicular fluid in cobalt-chromium alloy group at T₂ to T₄ increased(P < 0.05).The differences of the content of gingival crevicular fluid in titanium group among T₁-T₃ and T₄ were not statistically significant(P>0.05).The GI, PD and gingival crevicular fluid in titanium group at T₂ to T₄ were lower than those in cobalt-chromium alloy group(P < 0.05 to P < 0.01).Compared with T₀, the levels of MDA and IL-6 in gingival crevicular fluid in two groups at T₃ to T₄ increased, while the levels of SOD and GST decreased(P < 0.05 to P < 0.01).The levels of IL-6 in gingival crevicular fluid at T₃ to T₄ in titanium group were lower than those in cobalt-chromium alloy group, but the levels of GST were higher than those in cobalt-chromium alloy group(P < 0.05 to P < 0.01).ConclusionsAs time going, both titanium porcelain crown and cobalt-chromium alloy porcelain crown can affect the periodontal tissue, but the effect of titanium porcelain crown is weaker than that of cobalt-chromium alloy porcelain crown.