SPECT脑血流及介入显像在痴呆诊断中的临床应用进展

局部脑血流SPECT显像可以在生理及病理情况下了解脑组织的血流灌注,评价其功能情况,结合介入显像可以评价脑血管的储备功能。局部脑血流显像对某些类型的痴呆可以明确其病因学,从而对其进行早期诊断、早期治疗及早期预防,使部分痴呆患者康复或缓解,尤其是在血管性和阿尔茨海默痴呆(早老性痴呆)的诊断和鉴别诊断中具有重要的临床价值。

Clinical advances of SPECT rCBF and interventional imaging applied in the diagnosis of dementias

Brain perfusion SPECT is a functional and noninvasive neuroimaging technique that allow the investigation of physiological and physiopathological events in the human brain,including cerebral perfusion and function.Interventional rCBF imaging can also evaluate cerebrovascular reserve.In clinically,rCBF imaging play an important role in the diag-nosis and differential diagnosis of dementias,especially vascular and Alzheimer's dementia.If etiology of some types of dementias is determined so that it can be early diagnosed,treated and taken prevention;the partial patients with demen-tia can get recovery or remission.