部分脾栓塞治疗自身免疫性溶血性贫血

目的 :观察部分脾栓塞治疗自身免疫性溶血性贫血的效果。方法 :电视透视下经右股动脉插管至脾动脉分支 ,先注入造影剂观察脾脏大小 ,然后注入无菌明胶海绵 ,再注入造影剂观察栓塞面积。栓塞面积为脾脏的 5 0 %～80 %。结果 :5例病人均于术后 3d血红蛋白开始上升 ,一般在 1mon左右升至 10 0g/L以上。除 1例合并脾脓肿外 ,其余 4例仅伴轻微腹痛、发热。结论 :部分脾栓塞治疗自身免疫性溶血性贫血有比较满意的疗效 ,且可避免全脾切除或全脾栓塞带来的一系列副作用。

Partial splenic embolization for autoimmune hemolytic anemia

Objective: To investigate the effect of partial splenic embolization in treatment of autoimmune hemolytic anemia. Methods: A catheter was inserted from right femoral artery to the splenic artery branch,in monitoring of X ray.First a preliminary contrast was injected. second a second contast injection was given to observe the size of spleen, third the sterilized gelatin sponge was injected.Finally a second contrast injection was given to estimate the embolized area,which was about 50%-80% of spleen.Results: Blood hemoglobin level increased from 3 day after operation and reached more than 100g/L within one month.Except splenic abscess which occurred in one patient, the other four patients had only a mild abdominal pain and a slight fever.Conclusion: Partial splenic embolization is a satisfactory procedure for treatment of autoimmune hemolytic anemia, Which can avoid the risk of severe side effects of splenectomy and full splenic embolization.