Repeated fecal microbiota transplantation in a child with ulcerative colitis |
| |
| Authors: | Hirotaka Shimizu Katsuhiro Arai Jun Abe Kazuhiko Nakabayashi Takako Yoshioka Kenji Hosoi Makoto Kuroda |
| |
| Affiliation: | 1. Division of Gastroenterology, National Center for Child Health and Development, Tokyo, Japan;2. Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, Japan;3. Department of Maternal‐Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan;4. Department of Pathology, National Center for Child Health and Development, Tokyo, Japan;5. Pathogen Genomics Center, National Institute of Infectious Diseases, Tokyo, Japan |
| |
| Abstract: | We report the case of an 11‐year‐old girl with ulcerative colitis refractory to conventional therapy, who was subsequently treated successfully with repeated fecal microbiota transplantation (FMT). The patient was steroid dependent despite several infliximab treatments, and colectomy was proposed to improve quality of life. After repeated FMT, she was able to maintain remission with on minimal dose of steroid. Although her fecal microbiota was dysbiotic before FMT, it was restored to a similar pattern as the donor after repeated FMT. |
| |
| Keywords: | child fecal microbiota transplantation inflammatory bowel disease pediatric ulcerative colitis |
|
|
