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脂多糖对胆汁分泌的影响
引用本文:金鹤万 Jae-Woon CHOI 等. 脂多糖对胆汁分泌的影响[J]. 延边医学院学报, 2001, 24(4): 256-259
作者姓名:金鹤万 Jae-Woon CHOI 等
作者单位:[1]延边大学护理学院外科学教研室,吉林延吉133000 [2]韩国忠北大学校医科大学医院外科,忠清北道,清州361-763
摘    要:
[目的 ]通过脂多糖对胆汁分泌的影响实验 ,初步探讨引起肝功能障碍及肝内结石形成的机理 .[方法 ]在麻醉状态下 ,直接往实验动物肝内注入脂多糖等实验药物 ,测定相关数据 .[结果 ]脂多糖对胆汁分泌有抑制作用 ,并对胆汁酸、磷脂浓度有降低作用 ,而对胆红素、钙的浓度无显著作用 .[结论 ]脂多糖对胆汁分泌有明显作用 ,对诱发肝功能障碍及形成肝内胆结石有一定的影响

关 键 词:胆结石症  胆汁郁积  缩胆囊素  
文章编号:1000-1824(2001)04-0256-04
修稿时间:2001-10-26

Effects of lipopolysaccharide for biliation
JIN He-wan ,JIN Can ,Jae-Woon CHOI. Effects of lipopolysaccharide for biliation[J]. Journal of Medical Science Yanbian University, 2001, 24(4): 256-259
Authors:JIN He-wan   JIN Can   Jae-Woon CHOI
Affiliation:JIN He-wan 1,JIN Can 1,Jae-Woon CHOI 2
Abstract:
OBJECTIVE To primary study the mechanism of hypohepatia and intrahepatic lithiasis by through experiment effects of lipopolysaccharide for biliation. METHODS The lipopolysaccharide and other experimental medicine were directly injected into the liver of experimental animals under anaesthesia and the related data were measured. RESULTS The lipopolysaccharide could decrease the bile secretion and concentration of bile acid and phosphorus lipid, but had no effects for the concentration of bilirubin and calcium in the blood. CONCLUSION The lipopolysaccharide have a significant effects for the biliation and some effects for inducing the hypohepatia and forming of intrahepatic lithiasis.
Keywords:cholelithiasis  biliary stasis  cholecystokinin  cats
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