全身炎症反应综合征对恶性阻塞性黄疸患者预后的影响（附152例临床分析）

目的：提高恶性阻塞性疸患者全身炎症反应综合征与多器官功能障碍综合征关系的认识，探讨MODS的防治策略。方法：分析152例恶性阻塞性黄疸患者SIRS的临床资料，患者至少符合2项SIRS诊断标准，包括发热，体温过低，心动过速、呼吸急促或白细胞计数异常。结果术前出现SIRS者58例，发生率38．1％，其后MODS发生率36．2％，死亡13．8％，MODS中胃肠功能衰竭最常见，随着SIRS标准项目的增加MODS的比例也增加，但差异不显著（P＞0．05）。结论：早期诊断SIRS，积极调控机体炎症反应，是改善亚性阻塞性黄疸患者预后的关键。

Effect of systemic inflammatory response syndrome and multiple organ dysfunction syndrome on patients with malignant obstructive jaundice (report of 152 cases)

Objective To explore the effect of systemic inflammatory response syndrome and multiple organ dysfunction syndrome on patients with malignant obstructive jaundice,and probe the therapeutic strategies.Methods The clinical date of 152 patients accepted by our hospital from January 1995 to December 1999 were analyzed.The patients met at least two of the criteria for SIRS such as fever,hypothermia,tachycardia or abnormal white blood cell count.Results 58(38.1%)of the 152 patients investigated met two or more of the criteria for SIRS.The mobidity of SIRS was 38.1%,afterwards the morbidity of MODS was 36.2% and the mortality of the patients with SIRS was 13.8%.The most common syndrome was Gastrointestinal organ dysfunction.The proportion of patients suffering from MODS increased with the number of SIRS criteria that the patients met,but there was no statistical significance(P>0.05) Conclusion The authors concluded that the outcome of the patients with malignant obstructive jaundice can be improved on condition that SIRS is early diagnosed and the body inflammatory response is properly regulated.