Comparison of Human Eosinophils from Normals and Patients with Eosinophilia |
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| Authors: | David A. Bass William H. Grover Jon C. Lewis Pamela Szejda Lawrence R. DeChatelet Charles E. McCall |
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| Affiliation: | Department of Medicine, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27103;Department of Biochemistry, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27103;Department of Pathology, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27103 |
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| Abstract: | ![]()
Previous studies of the biochemistry and physiology of eosinophils have relied upon cells obtained from patients with eosinophilia (EE). It is unknown whether such cells might have been activated or partially exhausted by the pathological state causing eosinophilia. We examined cell surface charge, membrane transport of deoxyglucose, activation of lyso-somal acid phosphatase, and oxidative metabolism to provide a profile to compare EE with purified normal eosinophils (NE) and normal neutrophils. |
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