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Anti‐aging and hydration efficacy of a cross‐linked hyaluronic acid microstructure patch |
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| Authors: | Ye Jin Lee Hak Tae Kim Woo Jin Lee Sung Eun Chang Mi Woo Lee Jee Ho Choi Chong Hyun Won |
| Affiliation: | 1. https://orcid.org/0000-0002-3032-2428;2. Department of Dermatology, Kyunghee University hospital at Gangdong, Seoul, Republic of South Korea;3. Ye Jin Lee, Department of Dermatology, Kyung Hee University Hospital at Gangdong, 23, Kyung Hee Dae‐ro, Dongdaemun‐gu, Seoul 02447, Republic of South Korea.;4. Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of South Korea |
| Abstract: | This study evaluated the safety and efficacy of biodegradable microstructure patches composed of cross‐linked hyaluronic acid (CLHA). A primary skin irritation test showed that the CLHA patches were not an irritant, whereas a clinical study showed that application of single CLHA patches significantly improved skin hydration at the periorbital region for 3 days and at the nasolabial fold for 6 days. Patch application also improved superficial wrinkles at the periorbital region for 3 days and at the nasolabial fold for 1 day. The absence of side effects indicated that application of these CLHA microstructure patches is both safe and convenient for moisturization and anti‐wrinkle effects. |
| Keywords: | anti‐aging hyaluronic acid microstructure patch |