Antistaphylococcal activity of pentamidine. |
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| Authors: | M D Libman M A Miller G K Richards |
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| Affiliation: | McGill University, Montreal General Hospital, Quebec, Canada. |
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| Abstract: | Pentamidine isethionate was bacteriostatic against Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus sanguis, Micrococcus sp., and Candida albicans. S. aureus was inhibited by concentrations of 16 to 64 micrograms/ml and killed by 64 to greater than or equal to 128 micrograms/ml. Staphylococcal killing was consistently greater in the presence of cations and was unaffected by methicillin resistance. |
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