大剂量静脉滴注丙种球蛋白防止川崎病患儿冠状动脉损害的效果评价及护理

目的探讨大剂量静脉滴注丙种球蛋白防止川崎病患儿冠状动脉损害的效果。方法将82例川崎病患儿依据治疗方法分为观察组和对照组各41例，观察组患儿采用大剂量丙种球蛋白冲击治疗，对照组应用常规用量进行治疗。对照组采取常规护理，观察组在对照组的基础上按症状实施针对性的护理措施。比较2组的治疗及护理效果。结果观察组发生冠状动脉扩张1例，对照组发生8例，观察组发生率显著低于对照组。主要观察指标如发热、淋巴结肿大及皮肤黏膜改变的恢复时间观察组明显较对照组缩短。结论良好细致的护理和健康教育指导，可增加患儿及家属对川崎病的了解，积极配合医疗各个环节，可减少并发症，加快疾病康复。

Effect of intravenous infusion of high dose gamma globulin therapy on preventing Kawasaki disease children from coronary artery damage and nursing

Objective To explore the effect and nursing of high dose gamma globulin therapy on preventing Kawasaki disease children from coronary artery damage. Methods 82 cases of children with Kawasaki disease were divided into two groups according to the treatment methods, each with 41 cases. The observation group was treated by high dose shock treatment of gamma globulin, the control group was given conventional dosage of gamma globulin. The control group received routine nursing care. The observation group was given targeted nursing measures according to the symptoms on the basis of the control group. The treatment and nursing effect were compared between two groups. Results 1 cases of coronary artery di- latation appeared in the observation group, while 8 cases in the control group, the difference was statistically significant. The recovery time of main observation index such as fever, lymphadenopathy, skin and mucous membrane alterations was significantly shorter in the observation group than the control group, the differ- ences were statistically significant. Conclusions Careful nursing and health education guidance can in- crease the understanding of disease for Kawasaki disease children and their families, make them cooperate with medical work actively in order to reduce the complication and accelerate recovery.