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Thyroid function in a population of children with attention deficit hyperactivity disorder |
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| Authors: | J VALENTINE E ROSSI P O'LEARY TS PARRY JJ KURINCZUK P SLY |
| Affiliation: | Department of Developmental and Rehabilitation Medicine, Princess Margaret Hospital for Children;Department of Clinical Biochemistry, Queen Elizabeth II Medical Centre;State Child Development Centre and Child Health Research;TVW Telethon Institute for Child Health Research |
| Abstract: | To determine the prevalence of thyroid hormone abnormalities and generalized resistance to thyroid hormone in a population of children with attention deficit hyperactivity disorder (ADHD) as compared to reference ranges determined from a control population and hence to determine if routine thyroid hormone screening in children with non-familial ADHD is indicated. Method:Children attending the State Child Development Centre in Perth, Western Australia with ADHD, as defined by the Diagnostic and Statistical Manual of Mental Disorders (fourth edition) provided the study population. The control population consisted of 353 normal children with a history of allergy in whom radioallergosorbent (RAST) testing was being performed. Results:The prevalence of thyroid hormone abnormalities in the study population was 2.3% (95% CI 0.6%, 5.7%). There were no cases of generalized resistance to thyroid hormone. The prevalence of thyroid hormone abnormalities in the general population of children and adolescents has been reported to vary between 1 and 3.7%. Conclusion:Routine thyroid hormone screening is not indicated in children with non-familial ADHD. |
| Keywords: | attention deficit hyperactivity disorder thyroid |