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A case of pulmonary cavernous hemangioma: immunohistological examination revealed its endothelial cell origin
Authors:Kase M  Sakamoto K  Yamagata T  Watanabe K  Kunikane H  Okamoto H  Nagatomo A
Affiliation:Department of Thoracic Surgery, Yokohama Municipal Citizen's Hospital, Japan.
Abstract:
A 29-year-old woman was referred to our hospital for an abnormal shadow on chest roentgenogram. She had no symptom but its shadow was pointed out about 20 years ago. Chest CT scan showed a sharply demarcated homogenous mass measured 10 x 10 mm in the S4 segment. The tumor was resected with video-assisted thoracoscopic surgery under CT-guided marking wire inserted. Microscopic examination suspected cavernous hemangioma. Immunohistological staining demonstrated most lining cells of the cavernous structure stained positively for von Willebrand factor antibody, which suggests that this tumor was associated with endothelium. Then we decided that this tumor was pulmonary cavernous hemangioma.
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