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| 大肠癌新生淋巴管研究进展 | |
| 引用本文： | Li LR,Wan DS. 大肠癌新生淋巴管研究进展[J]. 癌症, 2006, 25(3): 382-384 |
| 作者姓名： | Li LR Wan DS |
| 作者单位： | 华南肿瘤学国家重点实验室,广东,广州,510060;中山大学肿瘤防治中心腹科,广东,广州,510060;华南肿瘤学国家重点实验室,广东,广州,510060;中山大学肿瘤防治中心腹科,广东,广州,510060 |
| 摘 要： | 大量的研究发现恶性肿瘤和瘤周组织内存在新生的淋巴管,新生的淋巴管密度和淋巴管标记物的表达强度均与淋巴结转移密切相关,这为揭示恶性肿瘤淋巴道转移机制和开发淋巴管靶向治疗提供了重要的研究途径。目前,肿瘤新生淋巴管的研究尚处于初始阶段,本文对其在大肠癌淋巴转移研究中的进展和存在的问题作一综述。 |
| 关 键 词： | 结直肠肿瘤 新生淋巴管 血管内皮生长因子 |
| 文章编号： | 1000-467X（2006）03-0382-03 |
| 收稿时间： | 2005-03-24 |
| 修稿时间： | 2005-03-242005-05-09 |
Advance in lymphangiogenesis of colorectal carcinoma |
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| Li Li-Ren,Wan De-Sen. Advance in lymphangiogenesis of colorectal carcinoma[J]. Chinese journal of cancer, 2006, 25(3): 382-384 | |
| Authors: | Li Li-Ren Wan De-Sen |
| Affiliation: | 1. State Key Laboratory of Oncology in South China, Guangzhou , Guangdong , 510060, P. R. China ;2. Department of Abdominal Surgery, Cancer Center, Sun Yat-sen University, Guangzhou , Guangdong , 510060, P. R. China |
| Abstract: | Lymphangiogenesis has been found in the parenchymatous and surrounding tissues of many malignancies. The density of neogenetic lymphatics and the expression levels of molecular markers of lymph duct are closely related to lymphatic metastasis. The study on lymphangiogenesis has become an important way to discover the mechanism of lymphatic metastasis and explore lymphatic targeting therapy; however, it is still at a primary phase in present. This article mainly reviewed the advance and the problems in the study on lymphangiogenesis of colorectal carcinoma. |
| Keywords: | Colorectal neoplasms Lymphangiogenesis Vascular endothelial growth factor |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |