健肝软坚丸治疗肝纤维化临床研究

目的:观察健肝软坚丸治疗肝纤维化的临床疗效。方法:将68例就诊的肝纤维化患者随机分为治疗组34例和对照组34例,两组患者均采用常规保肝支持治疗,治疗组加用健肝软坚丸治疗,对照组加用大黄虫丸治疗。观察治疗前后两组患者肝功能、肝纤维化四项、肝、脾形态等指标变化情况,评价临床疗效。结果:两组患者治疗后肝功能、肝纤维化四项及彩超下肝脾形态变化情况与治疗前比较,差异均有统计学意义(P0.05);治疗组有效率为94.11%,对照组有效率为79.41%,两组比较,差异有统计学意义(P0.05)。结论:健肝软坚丸治疗肝纤维化临床疗效显著,可改善患者肝功能、肝纤维化四项指标及超声表现,具有较好的抗肝纤维化作用。

Clinical Study of Jiangan Ruanjian Pill in Treatment of Hepatic Fibrosis

Objective:To observe the clinical effect of Jiangan Ruanjian Pill in treatment of Hepatic fibrosis.Methods:Sixty-eight patients with Hepatic fibrosis were randomly divided into treatment group (34 cases) and control group (34 cases).On the basis of general treatment,the two groups were treated with Jiangan Ranjian Pill and Dahuang Zhechong Pill.The changes of liver function,liver fibrosis,the shapes of liver and spleen were observed before and after treatment,and the clinical curative effect was evaluated.Results:The changes of liver function,liver fibrosis and liver and the shapes of spleen were significantly different between the two groups after treatment,and the treatment group was better than the control group (P ＜ 0.05);The effective rate of the treatment group was 94.11％,which was significantly different from that (79.41％) of the control group (P ＜ 0.05).Conclusion:Jiangan Ruanjian Pill is effective in treatment of Hepatic fibrosis,which can improve the liver function and the four Hepatic fibrosis indexes in patients with liver fibrosis and has a good anti-Hepatic fibrosis effect.