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脑损害患者的高级功能障碍与P300对比研究
引用本文:任惠,许虹,弓少霞,颜琳,刘磊,匡秀.脑损害患者的高级功能障碍与P300对比研究[J].昆明医学院学报,2000,21(1):73-75.
作者姓名:任惠  许虹  弓少霞  颜琳  刘磊  匡秀
作者单位:明医学院第一附属医院神经内科,昆明,650032
基金项目:云南省青年科学基金!95C137Q
摘    要:对68例不同病因的脑损害患者进行智商、记忆商、失认症及P300检查,其中脑梗塞34例,帕金森病18例,多发性硬化16例,并与51例年龄,性别和利手相匹配的正常人比较。结果脑损害各组患者的N2及P3波峰潜伏期较对照组显著延长,P3波幅显著降低。

关 键 词:脑梗塞  震颤性麻痹  多发性硬化  事件相关电位

A Comparative Study of Advanced Nervous Disorder with P300 in Brain Damaged Patients
REN Hui,XU Hong,GONG Shao-xia,YAN Lin,LIU Lei,KUANG Xiu.A Comparative Study of Advanced Nervous Disorder with P300 in Brain Damaged Patients[J].Journal of Kunming Medical College,2000,21(1):73-75.
Authors:REN Hui  XU Hong  GONG Shao-xia  YAN Lin  LIU Lei  KUANG Xiu
Abstract:We examinated IQ,MQ,Agnosia and P 300 of 68 patients damaged in brain with different pathogeny. These cases include 34 cerebral infarction,18 Parkinson Disease,16 multiple sclerosis and they were compared with 51 normal people who were matched on age,sex and handedness. Result: PL in N 2 and P 300 of brain damaged group was significantly longer than that of control group ( P <0 01),and amplitude of P 3 was significantly decreased ( P <0 05).IQ,MQ and PL of N 2 and P 3 showed significantly negative correlation ( P <0 01).Drawing recognition,decomposing drawing,repeat recognition and repeat indication compared with P 3PL were significantly negative correlation and amplitude of P 3 showed significantly negative correlation with drawing cognition. The result suggests that cognition disorders are different in brain damaged patients. And P 3PL is a sensitive indicatrix.
Keywords:Cerebral infarction  Parkinson Disease  Multiplesclerosis  Event relatived potential  Intellegence  Recognition  Memory
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