慢性萎缩性胃炎虚寒证与郁热证舌苔超微结构变化

应用电子显微镜技术对慢性萎缩性胃炎(CAG)虚寒证(Ⅰ型)与郁热证(Ⅱ型)舌脱落细胞进行检测。观察发现:CAGI 细胞器、桥粒残留较 CAGⅡ多(P<0.05),CAGⅡ张力微丝、细胞表面结构破坏较 CAGI 显著(P<0.05)。同时发现 CAG 与胃癌在舌苔超微结构上变化的差异不明显,而与慢性浅表性胃炎(CSG)相比差异显著(P<0.05)。CAG舌苔超微结构的变化可能为 CAG 早期诊断和辨证提供一定的形态学依据。

The Ultrastrueture Changes of Tongue Coating in Chronic Atrophic Gastritis with Deficiency Cold or Stagnated Heat Syndromes

This paper reports the electron-microscopic observations of tongue exfoliated cells in 17 cases of chronic atrophic gastritis(CAG),14 cases of chronic superficial gastritis.9 cages of gastric carcinoma with deficiency cold(DC)and stagnated heat(SH)syndromes,and 12 normal cases.The results by electron-microscope showed that cell-organs and desmosome remains in the DC group were significantly higher than those in the SH group(P<0.05).However,the damage degree on the tonifibrils and surface structure of cells in the SH group was more serious than those in the DC group (P<0.05).The observations by light and electron-microscope revealed that the changes of micro- structure and ultrastructure of tongue exfoliated cells in CAG did not distinguish from gastric carcinoma.But the changes in CAG was significantly different when compared with chronic superfi- cial gastritis(P<0.05).From the above,the authors consider that the changes of tongue exfoliated cells could provide some morphological basis for the early stage of diagnosis.