40岁以下肺癌病人放疗与化疗疗效分析

目的探讨40岁以下失去手术机会的肺癌病人放疗与化疗的疗效及影响预后因素。方法103例40岁以下病人单纯化疗45例，化疗与放疗综合治疗54例，单纯放疗4例。结果103例中CR23．3％（24／103），总有效率75．73％。1、2、5年生存率分别为52．37％、29．87％、7．8％，中位生存期15个月。结论放疗与化疗综合治疗疗效优于单一方法治疗；血清CEA、误诊及机体免疫功能为影响愈后的重要因素。

The analysis of radiotherapy and chemotherapy in patients under 40 years of age with lung cancer

Objective To analyze the clinical curative effect and the factors influencing prognosis of patients under 40 years of age with unresectable lung cancer in radiotherapy and chemotherapy. Methods A total of 103 cases with unresectable lung cancer were treated with radiotherapy and chemotherapy： chemotherapy sole in 45 cases, radiotherapy and chemotherapy in 54, and radiotherapy alone in4. Results Clinical curative effect of the patients was CR23. 30% （24/103）, PR52.43% （54/103）, CR＋PR75.73% （78/103）. The 1 -, 2-, 5-years survival rates were 52. 37%, 29. 87%, and 7.8% respectively, with a mean survival duration of 15 months. Conclusion The efficacy of radiotherapy and chemotherapy is better compared to any single therapy. The serum CEA level, misdiagnosis and immunity are the main factors influencing prognosis.