If the "adaptive" immune system can recognize a significant portion of the pathogenic universe to which the "innate" immune system is blind, then.. |
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Authors: | Cohn M |
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Affiliation: | Conceptual Immunology Group, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. cohn@salk.edu |
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Abstract: | ![]() The "adaptive" immune repertoire functionally recognizes pathogens (and their toxic products) that the "innate" defense system misses. This requires that the self-nonself discrimination and the regulation of effector output be dependent primarily on somatic learning mechanisms (i.e. on the somatically generated, large, random "adaptive" immune paratopes repertoire). |
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