| 氰戊菊酯对小鼠脑组织脂质过氧化及抗过氧化能力的影响 |
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| 引用本文： | 任春兰,陆荣柱,殷若元.氰戊菊酯对小鼠脑组织脂质过氧化及抗过氧化能力的影响[J].劳动医学,1995,12(2):4-6. |
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| 作者姓名： | 任春兰 陆荣柱 殷若元 |
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| 作者单位： | 镇江医学院 |
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| 摘 要： | 氰戊菊酯（Fen）染毒后小鼠脑组织中丙二醛（MDA），氧化型谷胱甘肽（GSSG）含量显著增加，同时还原型谷胱甘肽（GSH）含量下降，超氧化物歧化酶（SOD），谷胱甘肽过氧化物酶（GSH-PX）及过氧化氢酶（CAT）的活性均不同程度的下降，并呈一定的剂量反应关系。说明氰戊菊酯可能是脂质过氧化的引发剂。
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| 关 键 词： | 氰戊菊酯 小鼠 脑组织 脂质过氧化 抗过氧化能力 丙二醛 氧化型谷胱甘肽 杀虫剂 |
EFFECT OF FENVALERATE ON LIPID PEROXLDATION AND ANTIOXIDATION OF MOUSE BRAIN TISSUE |
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| Ren Chun-lan, Ru Yong-zu, Yin Ruo-yuan.EFFECT OF FENVALERATE ON LIPID PEROXLDATION AND ANTIOXIDATION OF MOUSE BRAIN TISSUE[J].Journal of Labour Medicine,1995,12(2):4-6. |
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| Authors: | Ren Chun-lan Ru Yong-zu Yin Ruo-yuan |
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| Abstract: | Observation was performed on the content of malanaldehyde(MDA),oxidative glutathione (GSSG),glutathione(GSH) and the activites of glutathione peroxidease(GSH-px),superoxide dismutase(SOD) and catalase(CAT) of brain tissue of mice exposed to fenvalerate. The reasults revealed that the levels of MDA and GSSG were remarkably higher and the activities of GSH-px,SOD, CAT and the contents of GSH were remarkably lower compared with the control group,A dose-reponse relationship was notioed.These results showed that Fen is an agent inducing lipid peroxidation. |
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| Keywords: | Fenvalerate Lipid peroxidation Autagonistic oxidation offect |
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