Effects of intracerebroventricular injections of 2-deoxy-D-glucose,d-glucose and xylose on operant feeding in pigs |
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Authors: | R.F. Parrott B.A. Baldwin |
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Affiliation: | ARC Institute of Animal Physiology, Babraham, Cambridge, UK USA |
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Abstract: | The effects, on operant feeding, of injection into the lateral cerebral ventricle of 50 μmoles CaCl2, 4 mmoles D-glucose, 2-deoxy-D-glucose (2DG) or xylose, or NaCl, have been studied in five pigs. All the sugars and CaCl2 were given in 1 ml of normal saline. Each of the sugar solutions produced transient drinking. Only CaCl2 and 2DG significantly increased food intake during the hour following injection. The results show that the mechanism by which the pig responds to intracerebroventricular 2DG is similar to that of the rat and different from that of the sheep. |
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Keywords: | Pigs Operant feeding 2DG Lateral cerebral ventricle |
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