高甘油三酯腰围表型青少年心血管危险因素分析

目的分析高甘油三酯腰围表型（Hw）青少年心血管危险因素状态。方法选取秦皇岛地区1665名13～15岁青少年进行流行病学调查，测量身高、体重、腰围（WC）、血压、空腹血糖（FPG）、血甘油三酯（TG）和高密度脂蛋白胆固醇（HDL—C）。HW定义为WC≥年龄、性别特异的80百分住点并且TG≥1．24mmol／L。括腰围及甘油三醋水平，分为A组：WC和TG均正常组IB组：单纯WC或TG高；C纽；WC和TG均高组。结果①HW患病率为7．0％，男、女分别为6．9％和7．2％，不同性别Hw患病率比较差异无统计学意义（X2=0．077，P=0。781）。②校正年龄、性别后应用协方差分析，三组间各指标比较差异均有统计学意义（P〈0．05）。应用LSD法进行两两比较，B组和C组体质量指数（BMI）、WC、收缩压（SBP）、舒张压（DBP）、FPG及TG水平均高于A组，HDL—C水平均低于A组（P〈0．05）。C组BMI、WC、SBP及TG水平高于B组，HDL—C水平低于B组（P〈0．05）。绩论HW青少年存在更为严重的代谢异常。HW是一种简单、便宜方法，可用于评价心血管危险因素的聚集情况。

ANALYSIS OF CARDIOVASCULAR RISK FACTORS IN ADOLESCENTS WITH HYPERTRIGLYCERIDEMA WAIST PHENOTYPE

Objective To analysis the cardiovascular risk factors in adolescents with hypertriglyceridema waist phenotype. Methods A crosssectional study was conducted in 1665 adolescents aged 13- 15 years. Height, weight, waist circumference, blood pressure, fasting plasma glucose （FPG）, triglyceride（TG） and highdensity lipoprotein cholesterol（HDL-C） were measured. The HW phenotype was defined as serum triacylglycerol concentrations≥1.24mmol/ L and waist circumference≥80 percentile for age and sex. Based on the level of WC and TG, the adolescents were divided into three groups： Group A with normal WC and TG; Group B with high WC or TG; Group C with high WC and TG. Results （1）The prevalence of the HW phenotype was 7. 0% . There was no significant difference in the prevalence of the HW phenotype between boys （6. 9%） and girls（7.2%）. After control for age and sex, adolescents in different groups had significant difference. Multiple comparisons were made by least significant difference（LSD） test, group B and C had significantly higher levels of BMI,WC,SBP,DBP,FPG and TG than those in group A, and lower HDL- C than that in group A （P〈0. 05）. Group C had significantly higher levels of BMI,WC,SBP and TG than those in group B, and lower HDL - C than that in group B （P〈0. 05）. Conclusion The HW phenotype could be used to predict for clustering the risk of Cardiovascular diseases in adolescents.