高危型人乳头瘤病毒在广西地区感染情况的调查分析

目的探讨高危型人乳头瘤病毒(HPV)在广西地区的感染情况。方法采用第2代杂交捕获技术混合检测13种高危型HPV-DNA,对26 796份女性宫颈分泌物标本的检测结果进行回顾性分析。结果广西地区高危型HPV感染率为17.94%,其中桂北地区HPV感染率最高,且各区域间比较差异有统计学意义(P0.05)。HPV感染的高峰年龄段在小于20岁、50~60岁、≥60岁,各年龄段HPV感染率比较差异有统计学意义(P0.05);HPV高病毒载量患者的比例为40.93%,且随着年龄的增长呈上升趋势。结论高危型HPV感染在广西地区存在地域和年龄差异,对高发地区、年龄段应重点监测,必要时对高病毒载量患者完善宫颈细胞学及组织学的检查。

Type high-risk human papilloma virus infection status of investigation and analysis in Guangxi region

Objective To discuss the high-risk human papillomavirus (HPV )infection in the Guangxi .Methods A total of 26 796 copies of the test results for female cervical secretions specimens were analyzed retrospectively from what the second-genera-tion hybrid capture technology mixed detect 13 kinds of high-risk HPV viral DNA .Results Infection rate was 17 .94% in Guangxi , and the infection of HPV in north was higher than other regions ,and the differences of regions had statistically significant (P<0 .05) .The peak age of infection in the Guangxi region was less than 20 years old ,50- <60 years old ,and equal or more than 60 years old .The differences among age groups was statistically significant(P<0 .05) .Patients constitute HPV infection Guangxi re-gion had high viral load for 40 .93% ,and high viral load constituent ratio rise with age .Conclusion The existence of high-risk HPV infection is regional different and age different in the Guangxi region ,to high-prone areas ,infection high age should focus on monito-ring ,high viral load in patients with complete cervical cytology and histology examination if necessary .